Research & Clinical Resources
Connecting Michigan families to the latest Fragile X research, clinical trials, and treatment centers.
FXAM is committed to advancing research and connecting our community with the best available clinical resources. Below you'll find information on Michigan's Fragile X clinic, national research registries, clinical trials, and our partnership with the National Fragile X Foundation.
Fragile X Clinics
Specialized clinical care for individuals with Fragile X Syndrome and associated disorders.
University of Michigan Fragile X Clinic
Appointments for evaluation and treatment of Fragile X Syndrome are available at the U of M Fragile X Clinic. Schedule by requesting a referral from your child's primary care physician.
East Ann Arbor Health and Geriatrics Center
Research & Clinical Trials
Find active studies, registries, and research resources for Fragile X.
Search for active Fragile X clinical trials across the United States.
Search "fragile X" →A leading nonprofit funding biomedical research aimed at finding effective treatments and a cure for Fragile X.
Visit FRAXA →Community and research news for families living with Fragile X.
Learn More →Key Research Articles
Peer-reviewed studies and clinical resources for families and providers.
- Advances in the Treatment of Fragile X SyndromeStudies of metabotropic glutamate receptor 5 pathway antagonists in animal models have demonstrated benefits in reducing seizures, improving behavior, and enhancing cognition.NIH / PubMed
- Autism Spectrum Disorder in Fragile X Syndrome: Co-occurring Conditions and Current TreatmentHalf of males and nearly 20% of females with FXS met DSM-5 criteria for ASD. The FXS+ASD group had higher prevalence of seizures, sleep problems, and behavior issues.Pediatrics / AAP
- Fragile X Spectrum DisordersReview focusing on phenotypes and genotypes of children with Fragile X Spectrum Disorder (FXSD).NIH / PubMed
- GeneReviews — FMR1 Related DisordersA publicly funded medical genetics information resource for physicians, healthcare providers, and researchers.NCBI GeneReviews
- Fragile X Premutation Disorders — Expanding the Psychiatric PerspectiveFragile X-associated psychiatric manifestations serve as a useful model for a molecular genesis of neuropsychiatric illness.NIH / PubMed
Quick Links
NFXF Community Partner
The Fragile X Association of Michigan is a proud National Fragile X Foundation (NFXF) Community Partner. The NFXF website is loaded with all the medical and technical information you need about Fragile X Syndrome, FXTAS, FXPOI, and related conditions.
FXAM provides scholarships to the NFXF International Fragile X Conference. Check our Events page for eligibility requirements and upcoming conference details.